GYN

UTERINE

  • GOG 0238 – A Randomized Trial of Pelvic Irradiation With or Without Concurrent Weekly Cisplatin in Patients with Pelvic Only Recurrence of Carcinoma of the Uterine Corpus
  • GOG 0275– A Randomized Phase III Study of Methotrexate or Dactinomycin in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia
  • GOG 0277- A Randomized Phase III Study of  Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

ENDOMETRIAL

  • RTOG 1203– A Randomized Phase III Study of Standard vs. Intensity-Modulated Pelvic Radiation Therapy For Post-Operative Treatment of Endometrial and Cervical Cancer
  • GOG 0286B– A Randomized Phase II/III Study of Paclitaxel/Carboplatin/Metformin Versus Paclitaxel/Carboplatin/Placebo as Initial Therapy forMeasurable Stage III or IVA, Stage IVB, or Recurrent Endometrial Cancer (Temporarily closed to accrual)

CERVIX

  • GOG 0263 – Randomized Phase III Clinical Trial of Adjuvant Radiation versus Chemoradiation in Intermediate Risk, Stage I/IIA Cervical Cancer Treated with Initial Radical Hysterectomy and Pelvic Lymphadenectomy
  • RTOG 1203– A Randomized Phase III Study of Standard vs. Intensity-Modulated Pelvic Radiation Therapy For Post-Operative Treatment of Endometrial and Cervical Cancer
  • RTOG 0724– A Randomized Phase III Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy
  • GOG 0274A Randomized Phase III Study of Adjuvant Chemotherapy Following Chemoradiation as Primary Treatment for Locally Advanced Cervical Cancer Compared to Chemoradiation Alone: The OUTBACK Trial

OVARIAN/FALLOPIAN TUBE

  • GOG 0213– A Randomized Phase III Study of Carboplatin and Paclitaxel (or Gemcitabine) with/or without Bevacizumab followed by Bevacizumab and Secondary Cytoreductuve Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary, and Fallopian Tube Cancer
  • GOG 0264– A Randomized Phase II  Study of Paclitaxel and Carboplatin vs. Bleomycin, Etoposide, and Cisplatin for Newly Diagnosed Advanced Stage and Recurrent Chemonaive Sex-Cord Stromal Tumors of the Ovary
  • GOG 0281- A Randomized Phase II/III Study to Assess the Efficacy of Trametinib in Patients with Recurrent or Progressive Low-Grade Serous Ovarian Cancer or Primary Peritoneal Cancer
  • NRG-GY001– A Randomized Phase II Trial of Cabozantinib (XL-184) (NSC#761968) in Women with Recurrent Clear Cell Carcinoma of the Ovary, Fallopian Tube, or Peritoneum

Vulvar

  • GOG 0270– Groningen International Study on Sentinel Nodes in Vulvar Cancer (GROINSS-V) II: An Observational Study

Metastatic

  • RTOG 0631– A Randomized Phase II/III Study of Image-Guided Radiosurgery/SBRT for Localized Spine Metastasis